Which two primary bile acids are converted by gut microbiota into secondary bile acids?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the ACVIM Small Animal Internal Medicine Exam to enhance your veterinary knowledge. Prepare with flashcards and multiple-choice questions, featuring hints and explanations. Ensure success in your exam journey!

Multiple Choice

Which two primary bile acids are converted by gut microbiota into secondary bile acids?

Explanation:
Primary bile acids produced by the liver are cholic acid and chenodeoxycholic acid. In the gut, resident microbiota deconjugate and perform 7α-dehydroxylation on these molecules to form secondary bile acids: deoxycholic acid comes from cholic acid, and lithocholic acid comes from chenodeoxycholic acid. This microbial transformation is how secondary bile acids are generated and circulated back to the liver. Conjugated forms like taurocholic and glycocholic acids are not the substrates for this conversion until they are deconjugated, and other options list either secondary bile acids or conjugated forms rather than the primary acids themselves.

Primary bile acids produced by the liver are cholic acid and chenodeoxycholic acid. In the gut, resident microbiota deconjugate and perform 7α-dehydroxylation on these molecules to form secondary bile acids: deoxycholic acid comes from cholic acid, and lithocholic acid comes from chenodeoxycholic acid. This microbial transformation is how secondary bile acids are generated and circulated back to the liver. Conjugated forms like taurocholic and glycocholic acids are not the substrates for this conversion until they are deconjugated, and other options list either secondary bile acids or conjugated forms rather than the primary acids themselves.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy