Which sites received cumulative WSAVA histopathology scores?

• A. Stomach and duodenum
• B. Ileum and colon
• C. Jejunum and ileum
• D. Liver and spleen

Answer: (B)

The WSAVA histopathology scoring framework provides standardized, semi-quantitative grades of mucosal inflammation for different parts of the GI tract. In many studies, researchers create a single, overall measure by summing the scores from specific distal GI sites to form a cumulative score. The ileum and colon are the sites most commonly combined for this purpose because they consistently reflect distal GI mucosal inflammation and offer comparable, practical data across cases. This makes the ileum and colon the pair used to derive a cumulative WSAVA histopathology score.

Stomach, duodenum, and jejunum are typically evaluated separately or with different site-specific considerations, and the liver and spleen are not part of the standard lower GI histopathology scoring in this context.