Which Patnaik grade has 0–2 mitotic figures per 400 high-power fields?

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Study for the ACVIM Small Animal Internal Medicine Exam to enhance your veterinary knowledge. Prepare with flashcards and multiple-choice questions, featuring hints and explanations. Ensure success in your exam journey!

Multiple Choice

Which Patnaik grade has 0–2 mitotic figures per 400 high-power fields?

Explanation:
Mitotic activity is a key feature used in the Patnaik grading of canine mast cell tumors. The three Patnaik grades range from well-differentiated (lowest proliferative activity) to poorly differentiated (highest proliferative activity). A count of 0–2 mitotic figures across 400 high-power fields indicates low proliferative activity, which fits the middle, intermediately differentiated category rather than the least differentiated or the most aggressive grade. Hence, this mitotic count best aligns with the Patnaik Grade II.

Mitotic activity is a key feature used in the Patnaik grading of canine mast cell tumors. The three Patnaik grades range from well-differentiated (lowest proliferative activity) to poorly differentiated (highest proliferative activity). A count of 0–2 mitotic figures across 400 high-power fields indicates low proliferative activity, which fits the middle, intermediately differentiated category rather than the least differentiated or the most aggressive grade. Hence, this mitotic count best aligns with the Patnaik Grade II.

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