Which of the following is true about ASVCP guidelines for reference intervals?

• A. They cover de novo reference intervals in veterinary species and other related topics
• B. They prescribe pharmacodynamic parameters
• C. They focus solely on canine reference values
• D. They exclude observational data

Answer: (A)

ASVCP guidelines are guidance for creating reference intervals in veterinary medicine, not about drug effects or species‑limited values. They explicitly cover de novo reference interval development across veterinary species and detail the study design, how to select a healthy reference population, recommended sample sizes, handling of outliers, and how to partition data by factors like age, sex, or species. They also address validation and transfer of intervals to other settings, and discuss how observational data or indirect approaches can be used appropriately within the framework. This makes the statement true: the guidelines encompass de novo reference intervals in veterinary species and related topics, rather than focusing narrowly on one species or on pharmacodynamics, and they do not exclude observational data outright.