Telangiectatic osteosarcoma has been associated with shorter survival in some studies.

• A. True
• B. False
• C. Not studied
• D. Not reported

Answer: (A)

Telangiectatic osteosarcoma is a high-grade variant that can behave more aggressively than typical osteosarcoma, and several studies have found shorter survival associated with this subtype. This may reflect its biologically aggressive nature and, at times, diagnostic challenges since the tumor’s blood-filled spaces can mimic benign lesions like aneurysmal bone cyst, potentially delaying definitive treatment. While accurate diagnosis and standard multimodal therapy can yield outcomes comparable to other high-grade osteosarcomas in some cases, the literature has documented poorer survival in other cohorts. Thus, the statement is supported by evidence from multiple studies.