In the subcutaneous MCT cohort, high mitotic count increased risk of death from MCT by approximately what HR?

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Study for the ACVIM Small Animal Internal Medicine Exam to enhance your veterinary knowledge. Prepare with flashcards and multiple-choice questions, featuring hints and explanations. Ensure success in your exam journey!

Multiple Choice

In the subcutaneous MCT cohort, high mitotic count increased risk of death from MCT by approximately what HR?

Explanation:
High mitotic activity in subcutaneous mast cell tumors is a strong predictor of poorer outcome, and survival analyses express this as a hazard ratio. In this subcutaneous MCT cohort, high mitotic count was associated with a hazard ratio of about 8.2, meaning the instantaneous risk of death from MCT at any given time was roughly eight times higher for dogs with high mitotic counts than for those with lower counts. This large effect size explains why the approximate value 8.2 is the best choice. The other numbers would imply much smaller or unrealistically large effects that don’t fit the study’s findings.

High mitotic activity in subcutaneous mast cell tumors is a strong predictor of poorer outcome, and survival analyses express this as a hazard ratio. In this subcutaneous MCT cohort, high mitotic count was associated with a hazard ratio of about 8.2, meaning the instantaneous risk of death from MCT at any given time was roughly eight times higher for dogs with high mitotic counts than for those with lower counts. This large effect size explains why the approximate value 8.2 is the best choice. The other numbers would imply much smaller or unrealistically large effects that don’t fit the study’s findings.

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